Phospho-ERK1 (T202/Y204) + ERK2 (T185/Y187) and Total ERK1/2 ELISA Kit
Product Details
Specifications
- Pre-Coated 96-well Strip Plate, 1 each
- Positive Control vial, 1 each
- anti-Pan Detection Antibody
- anti-Phos Detection Antibody
- Assay Diluent
- HRP-conjugated Secondary Antibody
- TMB Substrate, 12 ml
- Stop Solution, 8 ml
- 20X Wash Buffer, 25 ml
- 2X Lysis Buffer, 5ml
Additional Product Information
Extracellular signal-regulated kinase 1 (ERK1/p44), also known as mitogen-activated protein kinase 3 (MAPK3), and extracellular signal-regulated kinase 2 (ERK2/p42), also known as mitogen-activated protein kinase 1 (MAPK1), are part of a signal transduction pathway that begins with the small GTPase Ras and continues through a cascade of protein kinases that include Raf and MEK. Activation of this signaling pathway influences many cellular processes such as proliferation, differentiation and survival. ERK1 is very similar in sequence to ERK2/p42 and the activities of both ERK1 and ERK2 are usually considered together as total ERK activity. More recent evidence has shown that ERK1 and ERK2 are not functionally redundant and may have very different and specific roles.
Alternate Names
ERK1;ERK-1;ERT2;extracellular signal-regulated kinase 1;extracellular signal-related kinase 1;HS44KDAP;HUMKER1A;insulin-stimulated MAP2 kinase;MAP kinase 3;MAP kinase isoform p44;MAPK 1;MAPK 3;microtubule-associated protein 2 kinase;mitogen-activated protein kinase 3;P44ERK1;p44-ERK1;P44MAPK;p44-MAPK;PRKM3