Purified Recombinant Human IgA2, kappa
Product Details
Specifications
Antibody was produced by transient transfection in CHO cells.
Recombinant antibody was purified from cell culture supernatant using and affinity based immunosorbent.
Additional Product Information
IgA is an immunoglobulin that is typically dimeric and held together by a J-chain protein. IgA is typically found near the mucous membranes of the body, including the gut, respiratory system, eyes, and colostrum. Also exists in a secretory form (in mucosal regions) vs. serum IgA, which is found in serum. IgA exists in two subclasses, IgA1 and IgA2, both of which are essential components of mucosal immunity. Although they share similar immune functions, they differ in structure, distribution, and vulnerability to proteolytic enzymes. IgA1 is the main form found in the bloodstream, while IgA2 is more commonly present in secretions such as saliva, tears, and breast milk.
Applications
Used as a positive control in immunoassays.