Rabbit anti-CRTC1/TORC1 Recombinant Monoclonal Antibody [BLR389P]
Product Details
Specifications
Immunogen was a peptide representing a region between residue 584 and 634 of human CREB regulated transcription coactivator 1 (aka CRTC1) using the numbering given in entry NP_056136.2 (Gene ID 23373).
Additional Product Information
TORC1 (transducer of regulated CREB activity 1) is part of a family of CREB (cAMP response element-binding protein) coactivators that also includes TORC2 and TORC3. These proteins function to activate CREB-dependent transcription in response to cAMP and calcium signaling pathways. The TORC family of proteins has been shown to regulate transcription of PGC-1 alpha, a regulator of mitochondrial genes.
Alternate Names
CREB-regulated transcription coactivator 1;Mam-2;MAML2;Mastermind-like protein 2;MECT1;mucoepidermoid carcinoma translocated protein 1;TORC1;TORC-1;Transducer of CREB protein 1;transducer of regulated cAMP response element-binding protein (CREB) 1;Transducer of regulated cAMP response element-binding protein 1;WAMTP1
Applications
All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.
Western blots of cell lysates are performed using Goat anti-Rabbit IgG Heavy and Light Chain Antibody (A120-101P).
Western blots of immunoprecipitates are performed using Goat anti-Rabbit Light Chain HRP Conjugate (A120-113P) with 5% Normal Pig Serum (S100-020) added to the blocking buffer.